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Information on didactic, research and institutional assignments on this page are certified by the University; more information, prepared by the lecturer, are available on the personal web page and in the curriculum vitae indicated on this webpage.
Information
LecturerRasponi Marco
QualificationFull professor full time
Belonging DepartmentDipartimento di Elettronica, Informazione e Bioingegneria
Scientific-Disciplinary GroupIBIO-01/A - Bioengineering
Curriculum VitaeDownload CV (102.96Kb - 02/12/2019)
OrcIDhttps://orcid.org/0000-0002-2904-8652

Contacts
Office hours
DepartmentFloorOfficeDayTimetableTelephoneFaxNotes
Dipartimento di Elettronica, Informazione e Bioingegneria. Ed.21Quarto---TuesdayFrom 10:00
To 12:00
3377---Si prega di concordare l'incontro anticipatamente / Students are kindly asked to write an email and make an appointment
E-mailmarco.rasponi@polimi.it
Personal website---

Data source: RE.PUBLIC@POLIMI - Research Publications at Politecnico di Milano

List of publications and reserach products for the year 2026 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Journal Articles
Advances in sensor integration for real-time monitoring of joint-on-chips (Show >>)
An Innovative “Tooth‐On‐Chip” Microfluidic Device Emulating the Structure and Physiology of the Dental Pulp Tissue (Show >>)
Modular de- and re-construction of vascularized osteochondral tissues in an Organ-on-Chip dual-compartment platform (Show >>)


List of publications and reserach products for the year 2025 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Abstract in Atti di convegno
Development of a Heart-on-Chip model to investigate the role of MLIP in LMNA cardiomyopathy (Show >>)
Development of pathological Heart-on-Chip models to advance extracellular vesicle-based therapy for cardiac fibrosis and myocardial injury (Show >>)
Development of pathological Heart-on-Chip models to improve Extracellular Vesicle-based paracrine therapy against myocardial injury (Show >>)
Predicting melanoma immunotherapy outcomes using patient microbiota and a 3D mechanically active Gut-on-Chip platform (Show >>)
Journal Articles
A Compartmentalized Joint‐on‐chip (JoC) Model to Unravel the Contribution of Cartilage and Synovium to Osteoarthritis Pathogenesis (Show >>)
A compartmentalized microfluidic platform to investigate immune cells cross-talk in rheumatoid arthritis (Show >>)
An Organ‐on‐Chip Platform for Strain‐Controlled, Tissue‐Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis (Show >>)
Intercalated Disc Abnormalities Are Linked to Arrhythmias in Inflammatory Cardiomyopathy (Show >>)
Microfluidic device for islet conformal coating with a polyethylene glycol-based hydrogel: innovating cell immunoprotection strategies in type 1 diabetes (Show >>)


List of publications and reserach products for the year 2024 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Abstract in Atti di convegno
035 - Mechanically active Joint-on-chip models as advanced preclinical tools to test anti-OA therapies and dissect the cross-talk among different compartments in OA (Show >>)
A 3D mechanically-active gut-on-chip enables prediction of response of melanoma to immune checkpoint inhibitors based on fecal microbiome (Show >>)
A new microfluidic cartridge to prepare non-viral gene delivery complexes (Show >>)
An OsteoChondral-Unit-on-Chip to Unravel the Mechano-Pathology of Osteoarthritis (Show >>)
Assessing the feasibility of innovative Liver-on-Chip models for in vitro hepatotoxicity screening (Show >>)
Beating heart-on-chip as a tool to elucidate clinical phenotype of patients affected by genetic cardiomyopathies (Show >>)
Design and development of an Organ-on-Chip model to study the role of mechanical stimuli on cartilage development and pathological onset (Show >>)
Development and characterization of mechanical-stimulated atrial and ventricular 3D heart-on-chip models (Show >>)
Development of a 3D human in vitro model of idiopathic pulmonary fibrosis in a Lung-on-a-Chip device (Show >>)
Development of a tool to elucidate the clinical phenotype of patients affected by genetic cardiomyopathy in a 3D beating heart-on-chip platform (Show >>)
Development of an Organ-on-Chip model to unravel the role of mechanical cues on cartilage development and pathology (Show >>)
Exploiting compartmentalization to unravel the contribution of cartilage and synovium to osteoarthritis pathogenesis in a novel joint-on-chip platform (Show >>)
On-chip tracking of human mesenchymal cells gene expression profile to unravel mechanically driven chondrogenesis processes (Show >>)
Role of Mechanical Stimulation Using an In vitro Beating Chip in microRNA-mediated Reprogramming of Human Cardiac Fibroblasts into Induced Cardiomyocytes. (Show >>)
Poster
Development of a microfluidic platform to generate vascularized colorectal cancer spheroids on chip (Show >>)
Dynamic OoC with integrated pumping system for net unidirectional flow (Show >>)
Journal Articles
A gut-on-a-chip incorporating human faecal samples and peristalsis predicts responses to immune checkpoint inhibitors for melanoma (Show >>)
An Advanced Mechanically Active Osteoarthritis‐on‐Chip Model to Test Injectable Therapeutic Formulations: The SYN321 Case Study (Show >>)
Cholangiocarcinoma-on-a-chip: A human 3D platform for personalised medicine (Show >>)
Development of a Microfluidic Vascularized Osteochondral Model as a Drug Testing Platform for Osteoarthritis (Show >>)
Fibrotic extracellular matrix impacts cardiomyocyte phenotype and function in an iPSC-derived isogenic model of cardiac fibrosis (Show >>)
In Vitro Mechanical Stimulation to Reproduce the Pathological Hallmarks of Human Cardiac Fibrosis on a Beating Chip and Predict The Efficacy of Drugs and Advanced Therapies (Show >>)
In vitro models of the crosstalk between multiple myeloma and stromal cells recapitulate the mild NF-κB activation observed in vivo (Show >>)


List of publications and reserach products for the year 2023 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Abstract in Atti di convegno
A compartmentalized joint-on-chip model as tool to investigate cartilage-synovium interactions in early stages of osteoarthritis (Show >>)
Efficacy assessment of the novel combined anti-oa treatment syn321 in an advanced mechanically active osteoarthritis-on-chip model (Show >>)
Exploiting compartmentalization to unravel the contribution of cartilage and synovium to osteoarthritis pathogenesis in a novel joint-on-chip model (Show >>)
Investigating the contribution of cartilage and synovium to osteoarthritis development through a compartmentalized human joint-on-chip model (Show >>)
Poster
Bone Marrow on chip: unravelling mesenchymal-hematopoietic crosstalk (Show >>)
Intestinal epithelium on chip for drug absorption studies (Show >>)
Intestinal epithelium on chip for pharmacological studies (Show >>)
TOOTH ON A CHIP: a MPS to mimic innervated dental pulp and mineralised interface (Show >>)
Conference proceedings
A microfluidic platform to unravel immune cells cross-talk in rheumatoid arthritis (Show >>)
Design and validation of a microfluidic cartridge to prepare non-viral gene delivery complexes (Show >>)
Journal Articles
A method to generate perfusable physiologic-like vascular channels within a liver-on-chip model (Show >>)
Are slaughterhouse-obtained livers suitable for use in ex vivo perfusion research? (Show >>)
Cancer-on-chip: a 3D model for the study of the tumor microenvironment (Show >>)
Immunomodulatory biomimetic nanoparticles target articular cartilage trauma after systemic administration (Show >>)
LivHeart: A Multi Organ-on-Chip Platform to Study Off-Target Cardiotoxicity of Drugs Upon Liver Metabolism (Show >>)
Predicting human cardiac QT alterations and pro-arrhythmic effects of compounds with a 3D beating heart-on-chip platform (Show >>)


List of publications and reserach products for the year 2022 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Abstract in Atti di convegno
A COMPARTMENTALIZED JOINT-ON-CHIP MODEL TO UNRAVEL THE ROLE OF CARTILAGE AND SYNOVIUM IN OSTEARTHRITIS PATHOGENESIS (Show >>)
A MICROFLUIDIC PLATFORM TO INVESTIGATE THE CROSS-TALK BETWEEN IMMUNE CELLS IN RHEUMATOID ARTHRITIS (Show >>)
A compartmentalized joint-on-chip to unravel cartilage-synovium crosstalk in osteoarthritis (Show >>)
Evaluating immune cells interaction in rheumatoid arthritis through a novel microfluidic technology (Show >>)
Contributions on scientific books
Electromechanical Stimulation of 3D Cardiac Microtissues in a Heart-on-Chip Model (Show >>)
Mechanical Induction of Osteoarthritis Traits in a Cartilage-on-a-Chip Model (Show >>)
Organ-on-Chips for Studying Tissue Barriers: Standard Techniques and a Novel Method for Including Porous Membranes Within Microfluidic Devices (Show >>)
Photo and Soft Lithography for Organ-on-Chip Applications (Show >>)
Journal Articles
A Human Stem Cell-Derived Neurosensory-Epithelial Circuitry on a Chip to Model Herpes Simplex Virus Reactivation (Show >>)
A new microfluidic platform for the highly reproducible preparation of non-viral gene delivery complexes (Show >>)
Functional microvascularization of human myocardium in vitro (Show >>)
GZMKhigh CD8+ T effector memory cells are associated with CD15high neutrophil abundance in non-metastatic colorectal tumors and predict poor clinical outcome. (Show >>)
Normothermic Ex Vivo Liver Platform Using Porcine Slaughterhouse Livers for Disease Modeling (Show >>)
Physiologic flow-conditioning limits vascular dysfunction in engineered human capillaries (Show >>)
Selective Cerebrospinal Fluid Hypothermia: Bioengineering Development and In Vivo Study of an Intraventricular Cooling Device (V-COOL) (Show >>)
manifesti v. 3.13.7 / 3.13.7
Area Servizi ICT
18/04/2026