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Information on didactic, research and institutional assignments on this page are certified by the University; more information, prepared by the lecturer, are available on the personal web page and in the curriculum vitae indicated on this webpage.
Information
LecturerRaimondi Manuela Teresa
QualificationFull professor full time
Belonging DepartmentDipartimento di Chimica, Materiali e Ingegneria Chimica "Giulio Natta"
Scientific-Disciplinary SectorIBIO-01/A - Bioengineering
Curriculum VitaeDownload CV (2.27Mb - 02/02/2025)
OrcIDhttps://orcid.org/0000-0003-2585-7206

Contacts
Office hours
DepartmentFloorOfficeDayTimetableTelephoneFaxNotes
Chimica, Materiali e Ingegneria Chimica ---edificio 6, Torre Nord, secondo pianoMondayFrom 12:00
To 13:00
4306---to be confirmed via e-mail
E-mailmanuela.raimondi@polimi.it
Personal websitewww.nichoid.polimi.it

Data source: RE.PUBLIC@POLIMI - Research Publications at Politecnico di Milano

List of publications and reserach products for the year 2025 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Conference proceedings
Label-free multimodal nonlinear optical microscopy identifies markers of macrophage polarization (Show >>)
Profiling macrophage responses to biochemical stimuli via stimulated Raman scattering microscopy (Show >>)
Journal Articles
A 3D millifluidic model of a dermal perivascular microenvironment on a chip (Show >>)


List of publications and reserach products for the year 2024 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Abstract in Rivista
A 3D micro-structured millifluidic model of vascularized tissue regeneration in vitro. (Show >>)
In vitro modulation of macrophage phenotype by 3D custom-made micro scaffolds. (Show >>)
Conference proceedings
A new approach for the study of cell monolayers with Positron and Positronium Annihilation Spectroscopy leveraging on cell-sheet technology. (Show >>)
An implantable imaging window for guiding and observing in vivo responses to foreign bodies. (Show >>)
Epithelial to Mesenchymal Transition modulation in breast cancer cells: a frontier for new investigation approaches. (Show >>)
Implantable Micro-optics for label-free non-linear imaging (Show >>)
Leveraging Non-negative Matrix Tri-Factorization and Knowledge-Based Embeddings for Drug Repurposing: an Application to Parkinson's Disease (Show >>)
Non-linear excitation microscopy of live cells by using an implantable microscope objective-on-a-chip (Show >>)
Noninvasive Markers of Macrophage Polarization via Multimodal Nonlinear Optical Microscopy (Show >>)
Unlocking new potential in Epithelial-to-Mesenchymal transition research with custom 3D synthetic Niche-like substrate. (Show >>)
Journal Articles
A millifluidic bioreactor allows the long term culture of primary lymphocytes or CD34+ hematopoietic cells while allowing the detection of tumorigenic expansion (Show >>)
High dioptric power micro-lenses fabricated by two-photon polymerization (Show >>)
In vivo label-free tissue histology through a microstructured imaging window (Show >>)
Non-Negative Matrix Tri-Factorization for Representation Learning in Multi-Omics Datasets with Applications to Drug Repurposing and Selection (Show >>)
The Impact of 3D Nichoids and Matrix Stiffness on Primary Malignant Mesothelioma Cells (Show >>)
The molecular basis of the anticancer effect of statins (Show >>)
Zwitterionic nanoparticles for thermally activated drug delivery in hyperthermia cancer treatment (Show >>)


List of publications and reserach products for the year 2023 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Abstract in Rivista
3D micro scaffolds as a frontier tool to model the EMT phenotype in cancer cells. (Show >>)
A miniaturised imaging window to guide and image foreign body reactions in vivo. (Show >>)
An implantable microscope objective-on-a-chip for multiphoton imaging in vivo. (Show >>)
Design and prototyping of a synthetic eggshell for the ex ovo engineering of frontier models of microvascular physiopathology and advanced therapeutics. (Show >>)
Development of an in vitro platform to detect tumorigenic events in human Haematopoietic Stem Cells (hHSCs). (Show >>)
Development of an integrated in vitro-in silico model to predict the interaction of immune cells with solid cancers (Show >>)
Expansion culture of bone marrow-derived mesenchymal stem cells in the micro-scaffold Nichoid to treat pediatric lung disease. (Show >>)
Generation of 3D models of vascularized tissue in a millifluidic optically-accessible bioreactor. (Show >>)
Modulation of macrophage polarization induced in vitro by 3D microscaffolds. (Show >>)
Multiphysics three-dimensional model of a bioengineered haematopoietic platform for platelet production. (Show >>)
Optimization of the Nichoid microscaffold for the expansion culture of human adipose-derived mesenchymal stem cells. (Show >>)
The Nichoid Micro Scaffold as a Tool for Repurposing "Migrastatic" Drugs Exploiting Synthetic Lethality. (Show >>)
Patents
Implantable platform for imaging in-vivo (Show >>)
OPTICALLY ACCESSIBLE SYSTEM FOR STUDIES ON EMBRYONATED EGGS (Show >>)
Contributions on scientific books
Inference of Synthetically Lethal Pairs of Genes Involved in Metastatic Processes via Non-Negative Matrix Tri-Factorization (Show >>)
Conference proceedings
3D microstructured scaffold geometry drives mesenchimal stem cell phenotype (Show >>)
3D photopolymerized scaffold pore size regulates mesenchymal stem cell phenotype. (Show >>)
A synthetic embryonated avian eggshell computational modeled to predict the oxygen transport. (Show >>)
Combining big data with cell culture on the 3D nichoid to discover new therapeutic strategies against cancer. (Show >>)
Design and validation of an in vitro platform for lymphocytes recirculation in cancer immunotherapy applications (Show >>)
Development of a computational/experimental model of 3D vascularized tissues. (Show >>)
Development of an in vitro platform to detect tumorigenic events in human Haematopoietic Stem Cells (hHSCs) (Show >>)
Fabrication of Plano-convex Microlenses using Two-Photon Polymerization for Bioimaging with Non-Linear Excitation Microscopy (Show >>)
Laser microfabrication for optical sensing and imaging in vivo (Show >>)
Mechanobiology of cancer progression (Show >>)
Mechanobiology of cancer progression. (Show >>)
Micro-Fabricated Optics for Multiphoton Microscopy (Show >>)
Mini invasive imaging window to guide and image foreign body reactions in vivo. (Show >>)
Modeling how chemical energy is converted into actin based motility (Show >>)
Two photon polymerization of an implantable microscope objective for intravital microscopy. (Show >>)
Two-Photon Polymerization of an In-Vivo Multiphoton Imaging Window (Show >>)
Two-photon laser polymerized microlenses for nonlinear excitation microscopy of biological samples (Show >>)
Journal Articles
3D photopolymerized microstructured scaffolds influence nuclear deformation, nucleo/cytoskeletal protein organization, and gene regulation in mesenchymal stem cells (Show >>)
Bone Marrow Mesenchymal Stem Cells Expanded Inside the Nichoid Micro-Scaffold: a Focus on Anti-Inflammatory Response (Show >>)
Human gut epithelium features recapitulated in MINERVA 2.0 millifluidic organ-on-a-chip device (Show >>)
Identification of a novel pathway in sporadic Amyotrophic Lateral Sclerosis mediated by the long non-coding RNA ZEB1-AS1 (Show >>)
Microlenses fabricated by two-photon laser polymerization for cell imaging with non-linear excitation microscopy (Show >>)
Oxygen Sensing in Neurodegenerative Diseases: Current Mechanisms, Implication of Transcriptional Response, and Pharmacological Modulation (Show >>)
Unravelling the mechanotransduction pathways in Alzheimer's disease (Show >>)
Whole transcriptomic analysis of mesenchymal stem cells cultured in Nichoid micro-scaffolds (Show >>)


List of publications and reserach products for the year 2022 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Abstract in Atti di convegno
Development of a combined experimental/computational model of tissue regeneration in the miniaturized optically accessible bioreactor (MOAB). (Show >>)
Validation of an innovative millifluidic gut-on-a-chip to challenge the microbiota-gut-brain axis in vitro (Show >>)
Patents
Piattaforma impiantabile per l'imaging in vivo (Show >>)
Sistema otticamente accessibile per studi su uova embrionate (Show >>)
Contributions on scientific books
A Human Neurovascular Unit On-a-Chip (Show >>)
Conference proceedings
Tissue regeneration imaged in vivo using a miniaturized window for intravital nonlinear microscopy (Show >>)
Journal Articles
A Miniaturized Imaging Window to Quantify Intravital Tissue Regeneration within a 3D Microscaffold in Longitudinal Studies (Show >>)
Effect of 3D Synthetic Microscaffold Nichoid on the Morphology of Cultured Hippocampal Neurons and Astrocytes (Show >>)
On‐chip magnetophoretic capture in a model of malaria‐infected red blood cells (Show >>)
Patients' Stem Cells Differentiation in a 3D Environment as a Promising Experimental Tool for the Study of Amyotrophic Lateral Sclerosis (Show >>)
Pectin-based bioinks for 3D models of neural tissue produced by a pH-controlled kinetics (Show >>)
RNA Molecular Signature Profiling in PBMCs of Sporadic ALS Patients: HSP70 Overexpression Is Associated with Nuclear SOD1 (Show >>)


List of publications and reserach products for the year 2021 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Abstract in Atti di convegno
Mechanical characterization of lamin coiled coil 1B domain: from monomer to tetramer configuration. (Show >>)
The interaction between SUN1 and Nup153 may result in the transmission of external forces to the nuclear pore complex. (Show >>)
Conference proceedings
Micro structured tools for cell modeling in the fourth dimension (Show >>)
Journal Articles
Characterization of the Microflow Through 3D Synthetic Niche Microenvironments Hosted in a Millifluidic Bioreactor (Show >>)
Intracellular label-free detection of mesenchymal stem cell metabolism within a perivascular niche-on-a-chip (Show >>)
Neural precursor cells expanded inside the 3d micro-scaffold nichoid present different non-coding rnas profiles and transcript isoforms expression: Possible epigenetic modulation by 3d growth (Show >>)
Neural precursors cells expanded in a 3D micro-engineered niche present enhanced therapeutic efficacy in vivo (Show >>)
Phototoxicity induced in living HeLa cells by focused femtosecond laser pulses: a data-driven approach (Show >>)
RNA-seq Characterization of Sex-Differences in Adipose Tissue of Obesity Affected Patients: Computational Analysis of Differentially Expressed Coding and Non-Coding RNAs (Show >>)
RNA-seq dataset of subcutaneous adipose tissue: Transcriptional differences between obesity and healthy women (Show >>)
The nuclear import of the transcription factor MyoD is reduced in mesenchymal stem cells grown in a 3D micro-engineered niche (Show >>)
Transcriptional characterization of subcutaneous adipose tissue in obesity affected women highlights metabolic dysfunction and implications for lncRNAs (Show >>)
Transcriptome Analysis of Subcutaneous Adipose Tissue from Severely Obese Patients Highlights Deregulation Profiles in Coding and Non-Coding Oncogenes (Show >>)
α-Synuclein antisense transcript SNCA-AS1 regulates synapses- and aging-related genes suggesting its implication in Parkinson's disease (Show >>)
manifesti v. 3.9.3 / 3.9.3
Area Servizi ICT
24/04/2025